Cannabinoid Receptor
Cannabinoid Receptor
Cannabinoid receptors are currently classified into three groups: central (CB1), peripheral (CB2) and GPR55, all of which are G-protein-coupled. CB1 receptors are primarily located at central and peripheral nerve terminals. CB2 receptors are predominantly expressed in non-neuronal tissues, particularly immune cells, where they modulate cytokine release and cell migration. Recent reports have suggested that CB2 receptors may also be expressed in the CNS. GPR55 receptors are non-CB1/CB2 receptors that exhibit affinity for endogenous, plant and synthetic cannabinoids. Endogenous ligands for cannabinoid receptors have been discovered, including anandamide and 2-arachidonylglycerol.
Cannabinoid Receptor Isoform Specific Products
All Product Categories
-
Cannabinoid Receptor Inhibitors
(37)
View all products
-
Cannabinoid Receptor Agonists
(141)
View all products
-
Cannabinoid Receptor Antagonists
(76)
View all products
-
Cannabinoid Receptor Activators
(14)
View all products
-
Cannabinoid Receptor Modulators
(24)
View all products
-
Cannabinoid Receptor Chemical
(1)
View all products
-
Cannabinoid Receptor Inducer
(1)
View all products
-
Cannabinoid Receptor Degrader
(1)
View all products
-
Cannabinoid Receptor Controls
(2)
View all products
-
Cannabinoid Receptor Ligands
(13)
View all products
-
Cannabinoid Receptor Related Products (448)
Related Products (448)
-
Antibodies (1)
-
Cannabinoid Receptor Isoform Comparison
-
5-Fluoro PB-22 8-hydroxyisoquinoline isomer
0 ImagesCat. No.: HY-W768607CAS No.: 2365470-99-95-Fluoro PB-22 8-hydroxyisoquinoline isomer is structurally similar to known synthetic cannabinoids.
-
Δ8-THC Glucuronide
0 ImagesCat. No.: HY-150345CAS No.: 62667-60-1Δ8-THC Glucuronide is a phytocannabinoid metabolite.
-
6',7'-Epoxy cannabigerol
0 ImagesCat. No.: HY-170709CAS No.: 140381-46-06',7'-Epoxy cannabigerol is a phytocannabinoid metabolite.
-
Pregnenolone monosulfate sodium (Standard)
0 ImagesCat. No.: HY-110189RCAS No.: 1852-38-6Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium (Standard)Pregnenolone monosulfate (sodium) (Standard) is the analytical standard of Pregnenolone monosulfate (sodium). This product is intended for research and analytical applications. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.
-
11-Nor-9(R)-carboxy-hexahydrocannabinol
0 ImagesCat. No.: HY-170047CAS No.: 64663-38-3Synonyms: 11-Nor-9β-carboxy-HHC11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9β-carboxy-HHC) is structurally similar to known phytocannabinoids.
-
Δ9-THCP acetate
0 ImagesCat. No.: HY-170705CAS No.: 2829292-82-0Synonyms: Δ9-Tetrahydrocannabiphorol acetateΔ9-THCP acetate (Δ9-Tetrahydrocannabiphorol acetate) is structurally similar to known phytocannabinoids.
-
5-Fluoro PB-22 7-hydroxyquinoline isomer
0 ImagesCat. No.: HY-172037CAS No.: 1630756-70-55-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic cannabinoid.
-
10α-Hydroxy-exo-THC
0 ImagesCat. No.: HY-W716866CAS No.: 56986-42-6Synonyms: 10α-Hydroxy-Δ9'11-hexahydrocannabinol10α-hydroxy-exo-THC is a cannabinoid compound, a metabolite of Δ9-THC, and can be found in cannabis. 10α-hydroxy-exo-THC can serve as an analytical reference standard for cannabinoid compounds .
-
Rimonabant-d10 hydrochloride
0 ImagesCat. No.: HY-14137SCAS No.: 1044909-61-6Rimonabant-d10 (hydrochloride) is the deuterium labeled Rimonabant hydrochloride. Rimonabant hydrochloride (SR 141716A hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant hHydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
-
Cannabigerol diacetate
0 ImagesCat. No.: HY-150347CAS No.: 1040411-87-7Cannabigerol diacetate is structurally similar to known phytocannabinoids.
-
Cannabigerobutolic acid
0 ImagesCat. No.: HY-170746CAS No.: 2468125-68-8Synonyms: CBGBACannabigerobutolic acid (CBGBA) is structurally similar to known phytocannabinoids.
-
PSB-KD107
0 ImagesCat. No.: HY-138121CAS No.: 955121-65-0PSB-KD107 is an agonist of the cannabinoid activated orphan G-protein-coupled receptor GPR18, and PSB-KD107 has anti-inflammatory activity. PSB-KD107 can be used in the study of Duchenne muscular dystrophy.
-
MDMB-FUBINACA metabolite M1
0 ImagesCat. No.: HY-W756790CAS No.: 2693397-47-4MDMB-FUBINACA metabolite M1 is structurally classified as a synthetic cannabinoid.
-
Δ4(8)-iso-THC
0 ImagesCat. No.: HY-169041CAS No.: 23050-59-1Synonyms: Δ4(8)-IsotetrahydrocannabinolΔ4(8)-iso-THC (Δ4(8)-Isotetrahydrocannabinol) is structurally similar to known phytocannabinoids.
-
5Br-INACA
0 ImagesCat. No.: HY-W109442CAS No.: 1799421-04-75Br-INACA is a precursor in the synthesis of synthetic cannabinoids.
-
8(R)-Hydroxy-9(S)-Hexahydrocannabinol
0 ImagesCat. No.: HY-168791CAS No.: 36403-92-68(R)-Hydroxy-9(S)-Hexahydrocannabinol is a metabolite of hexahydrocannabinol (HHC).
-
Dehydrocannabifuran
0 ImagesCat. No.: HY-150335CAS No.: 56154-59-7Synonyms: 6-Methyl-9-isopropenyl-3-pentyldibenzofuran-1-olDehydrocannabifuran (6-Methyl-9-isopropenyl-3-pentyldibenzofuran-1-ol) is a phytocannabinoid derivative.
-
GW-405833 (Standard)
0 ImagesCat. No.: HY-110036RCAS No.: 180002-83-9Synonyms: L768242 (Standard)GW-405833 (Standard) is the analytical standard of GW-405833 (HY-110036). This product is intended for research and analytical applications. GW-405833 (L768242) is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. GW-405833 also exhibits non-competitive CB1 antagonist, exerting its analgesic and and anti-inflammatory effect through a CB1 receptor (rather than CB2) dependent mechanism. GW-405833 can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF).
-
11-Hydroxy-9(R)-hexahydrocannabinol
0 ImagesCat. No.: HY-168794CAS No.: 64663-39-411-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid metabolite.
-
10α-Hydroxy-Δ8-THC
0 ImagesCat. No.: HY-170702CAS No.: 24902-23-6Synonyms: 10α-Hydroxy-Δ8-tetrahydrocannabinol10α-Hydroxy-Δ8-THC (10α-Hydroxy-Δ8-tetrahydrocannabinol) is a phytocannabinoid.
